The key difference between loose and dense connective tissue is that loose connective tissue has loosely arranged fibres and cells in the matrix, while dense connective tissue has densely arranged fibres in the matrix.
There are four types of basic tissues in the human body: epithelial tissue, connective tissue, muscle tissue, and nervous tissue. Considering its structure and the wide variety of functions, the connective tissue is the most known diverse tissue out of all basic tissues. The structure of connective tissue varies from soft gel-like loose (areolar) connective tissue to hard bones. Presence of extracellular matrix with ground substances and fibres is the unique characteristic feature of this special tissue. Based on the types and relative abundance of cells as well as the organization of fibres and ground substances, connective tissue can be classified into several categories. Loose and dense connective tissues are two important categories among them.